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Tryptophan in Sleep: More Than Just Turkey

Feel sleepy after Thanksgiving? This guide explores the science of L-tryptophan, its role in serotonin and melatonin, and best food sources.

Published on October 13, 2024

Every Thanksgiving, the same myth gets passed around the dinner table: the post-meal drowsiness is caused by the tryptophan in the turkey. While there's a kernel of truth in this, the full story of this essential amino acid and its role in sleep is far more nuanced and fascinating.

L-tryptophan is a fundamental building block for a healthy sleep-wake cycle. This guide will explore the science of how your body converts tryptophan into the chemicals that help you relax and fall asleep, and provide a list of the best food sources to ensure you're getting enough of this vital nutrient.

The Tryptophan-to-Sleep Pathway

Tryptophan is an "essential" amino acid, which means your body cannot produce it on its own; you must get it from your diet. Its role in sleep is as a precursor in a critical biochemical pathway:

Tryptophan → 5-HTP → Serotonin → Melatonin

  • Serotonin: Tryptophan is first converted into 5-HTP, which is then used to create serotonin. Serotonin is a neurotransmitter crucial for mood regulation, feelings of well-being, and relaxation.
  • Melatonin: When darkness falls, your brain uses serotonin as the raw material to produce melatonin, the hormone that signals to your body that it's time to prepare for sleep.

Without enough tryptophan in your diet, your body can't produce enough serotonin, which in turn limits your ability to produce melatonin. This can lead to difficulty falling asleep and poorer mood.

"Tryptophan is the first domino in the chain reaction that leads to a restful night."

The Carbohydrate Connection: Why Turkey Isn't the Whole Story

So why does the turkey myth persist? Turkey does contain tryptophan, but not significantly more than other poultry. The real reason you feel sleepy after a Thanksgiving meal is the combination of tryptophan-rich protein with a large portion of carbohydrates (like potatoes, stuffing, and pie).

Here's the trick: tryptophan has to compete with other amino acids to cross the blood-brain barrier and get into your brain. When you eat carbohydrates, your body releases insulin. Insulin helps clear the other competing amino acids from your bloodstream, effectively giving tryptophan an "express lane" to the brain.

Best Food Sources of Tryptophan

To support your body's serotonin and melatonin production, focus on incorporating these tryptophan-rich foods into your diet, ideally paired with a healthy carb source.

  • Poultry: Turkey and chicken are excellent sources.
  • Nuts and Seeds: Pumpkin seeds, sesame seeds, almonds, and walnuts are all packed with tryptophan.
  • Dairy: Milk, cheese, and yogurt are good sources. A glass of warm milk before bed is a classic for a reason.
  • Oats: A fantastic choice for a bedtime snack, as it provides both tryptophan and the complex carbs to help it work.
  • Eggs: A versatile and nutritious source.
  • Legumes: Chickpeas, beans, and lentils are great plant-based options.
  • Bananas: They contain tryptophan and are also a good source of magnesium and potassium, which help relax muscles.

By ensuring your diet is rich in tryptophan and supporting it with smart carbohydrate choices, you provide your body with the essential building blocks for a night of deep, restorative sleep. For more ideas, see our general guide on sleep and diet.

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